Haemophilia

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Haemophilia is a genetic disorder which prevents the blood from clotting due to lack of essential clotting factors. These clotting factors are proteins that interact with platelets in the blood to help form clots that plug lacerations. Problems that arise for sufferers of haemophilia are elongated periods of bleeding due to the inabilty to clot, but also haemorrhaging from much more minor injuries and in may cases of sufferers of haemophilia, bleeding can arise with no known cause. Haemophilia is an X-linkedrecessive condition, women carry the gene and pass it down the female line in the family, whereas males will have the condition becasue there is no homologous region on the Y chromosome to counteract the effect of the recessive gene [1]. The gene for haemophilia runs in the British Royal Family. One type of haemophillia which is the most common is haemophillia A. Haemophillia A is deficient in Factor V111, an anti-clotting protein which is also known as AHF, anti-haemophillia factor. Moreover, the gene that causes haemophillia A is located at the X chromosome instead of Y chromosome. [2] 

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