Myosin light chain kinase

From The School of Biomedical Sciences Wiki
Revision as of 10:21, 25 November 2013 by Nnjm2 (talk | contribs) (Added some links)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Myosin light chain kinase (MLCK), is used in the contraction of smooth muscle. An increase in calcium ions activates the MLCK to phosphorylate the myosin regulatory chain. The phosphorylation of this chain causes the myosin tail to uncurl and therefore be able to form filaments within the smooth muscle, these can then interact with actin and contract the muscle [1].

References

  1. Beckers World of the Cell 8th ed 2012. Hardin J, Bertoni G, Kleinsmith L. San Francisco. Pearson Education Inc.