G0

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G0 is a specialized resting state. If a cell enters G0 it leaves the cell cycle and so stops progress through G1[1]. Cells may enter G0 due to an unfavourable enviroment or as a result of a lack of signals telling the cell to divide[2].

G0 length varies from days to years before the cell re-enters the cell cycle[3]. Some cells will remain in a state of G0 for the life time of the organism[4]. If conditons become favourable and the cell passes through the Start or restriction point then the cells will continue through the cell cycle regardless of changes in enviroment or lack of signals[5].

References

  1. Alberts B., Johnson A., Lewis J., Raff M., Robert K., Walter P., (2008) Molecular Biology of the Cell, 5th edition, New York: Garland Science, Pg 1055
  2. Alberts B., Johnson A., Lewis J., Raff M., Robert K., Walter P., (2008) Molecular Biology of the Cell, 5th edition, New York: Garland Science, Pg 1055
  3. Alberts B., Johnson A., Lewis J., Raff M., Robert K., Walter P., (2008) Molecular Biology of the Cell, 5th edition, New York: Garland Science, Pg 1055
  4. Alberts B., Johnson A., Lewis J., Raff M., Robert K., Walter P., (2008) Molecular Biology of the Cell, 5th edition, New York: Garland Science, Pg 1055
  5. Alberts B., Johnson A., Lewis J., Raff M., Robert K., Walter P., (2008) Molecular Biology of the Cell, 5th edition, New York: Garland Science, Pg 1055

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