Gram positive bacteria

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Bacteria can be categorised based upon their reaction to Gram stain, which is retained by cells with a thick layer of peptidoglycan on the outside of their cytoplasmic membrane; these cells are Gram-positive and stain purple. Bacteria which don't retain Gram stain are called Gram negative[1].

Gram-positive bacteria lack an outer membrane so are, on the whole, usually sensitive to beta-lactam antibiotics like penicillin, which interfere with the production of peptidoglycan, leaving the cytoplasmic membrane exposed, and the cell susceptible to lysis[2].

Bacteria belonging to the genus Staphylococcus are Gram-positive[3].


  2. Rang, H., Ritter, H., Flower, R., Henderson, G. (2016). Rang & Dale's pharmacology (Eighth ed.)
  3. Madigan, M., Bender, K., Buckley, D., Sattley, W., Stahl, D. (2019). Brock biology of microorganisms (Fifteenth edition, Global ed.)
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