From The School of Biomedical Sciences Wiki
Jump to: navigation, search

In chemical terms, ligands are ions or molecules which bind to a central metal ion. The ligands are electron donors, meaning they have free electrons by which they can form dative covalent bonds with the central metal ion. A common example of a ligand is water, which has two lone pairs of electrons on the oxygen atom which it is free to donate[1]. In biology, however, we mainly refer protein-bound ligands. These are molecules which simply form a set of weak non-covalent bonds with a protein. Collectively, these interactions bind the protein and substrate together[2].


  1. "Ligands" Chemicool dictionary. 12/4/2017 <//>
  2. Molecular biology of the cell. Fifth edition. B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter. 2008.
Personal tools