PH

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The negative logarithm of the hydrogen ion concentration, the pH, is expressed as follows:

pH = -log10 [H+]

The pH scale is a measure of hydrogen ion concentration that eliminates dealing with large powers of 10 and compresses a large range of concentrations onto a more convenient scale, between 1 and 14 as show in the figure below:

PH.png

Acid Dissociation

Strong acids are considered to be completely dissociated into ions in dilute solutions. However, weak acids (or bases) are partially dissociated in solution, and thus an equilibrium is established between the ions and the undissociated molecules.

This equilibrium can be represented by the equation:

[HA]<=>[H+]+[A-].

Where: [HA] is the concentration of undissociated molecules; [H+] is the concentration of hydrogen ions; and [A-] is the concentration of the conjugate base.

This equation can be rearranged to give a Ka value, which is a measure of how strong an acid is.

Ka= [H+][A-]/[HA]

Stronger acids will dissociate more and will have a higher Ka value [1].

Use of Ka values is not very useful, as the differences in dissociation are massive between strong and weak acids, and the values calculated can vary by many orders of magnitude. As is done with the pH scale, we take the negative log of the Ka value to give the pKa value [2].

pKa=-log10Ka

When: pKa=pH; the compound is said to be at it's equivalence point, as the concentration of H+ is equal to the concentration of HA.

References

  1. Elliot WH &amp;amp;amp;amp;amp; Elliot DC, 2009, Biochemistry and Molecular Biology p.38; Oxford
  2. Elliot WH &amp;amp;amp;amp;amp; Elliot DC, 2009, Biochemistry and Molecular Biology p.39; Oxford
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