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A Uniporter is a carrier protein that transports a single solute molecule in one direction across a plasma membrane. This is transported via Facilitated Diffusion which therefore means no energy input is required and that it relies solely on the diffusion gradient established either side of the membrane. As this is a carrier protein, it also exhibits specificity and so can only transport one type of solute across the membrane. An example of a Uniporter are the glucose transporters (or GLUT) which are used to control the levels of glucose in the blood [1]. H+ ATPase is another example of a Uniporter located in the cells within the stomach, involved in maintaining a constant pH by actively transporting excess hydrogen ions out of the cells[2].


  1. Hardin, J. Bertoni, G. Kleinsmith, Lewis J. (2012) "Beckers World of the Cell" 8th ed. San Francisco, Pearson, pg 203
  2. Buxbaum, E.B., 2007. Transport of Solutes across Membranes. Chapter 17, P 265. Fundamentals of Protein Structure and Function.

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