Vitamin A

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Vitamin A is otherwise known as retinol, which is an intermediary to retinal. or beta carotene. When it is in the form of retinal, this metabolite will act as a light absorbing molecule.

Vitamin A is also an essential component of retanoic acid which is a crucial signalling molecule especially during Early Organogenesis.

It is necessary for low light and colour vision, as it is found in the retina of the eye. Vitamin A is used in the treatment of Rhodopsin-related diseases. 

Night blindness and retinitis pigmentosa are two main health conditions associated with the defficiency of Vitamin A. This particular vitamin has an essential role in the ocular system of the body, however, the rate of cone photoreceptors degenerated can be slowed as the result of the use of oral supplements[1].

Deficiency is more common within developing countries particularly during infancy when they are not getting sufficient amounts in breast milk. Common symptoms include xerophthalmia, anaemia and increased susceptibility of infection[2][3].

References

  1. https://ommbid.mhmedical.com/content.aspx?bookid=971&sectionid=62662092&jumpsectionID=62662117
  2. https://ods.od.nih.gov/factsheets/VitaminA-HealthProfessional/
  3. Dryja, T.P, 2001; 235: Retinitis Pigmentosa and Stationary Night Blindness. Available at https://ommbid.mhmedical.com/content.aspx?bookid=971&sectionid=62662092&jumpsectionID=62662117 (last accessed 22/10/18
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