Heterozygous advantage: Difference between revisions
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= Introduction = | === Introduction === | ||
A heterozygous advantage is where carrying just one autosomal recessive mutant allele could provide a selective advantage to the individual, by providing protection from a disease, for example. This can explain why alleles which are lethal or deletarious in the homozygous form persist <ref>Evolution.berkeley.edu, (2014). The "bad" gene. [online] Available at: http://evolution.berkeley.edu/evolibrary/article/misconcep_04 [Last accessed on 22 November 2014]</ref>. | A heterozygous advantage is where carrying just one [[Autosomal_recessive_disease|autosomal recessive]] mutant [[Allele|allele]] could provide a selective advantage to the individual, by providing protection from a disease, for example. This can explain why alleles which are lethal or deletarious in the [[homozygous|homozygous]] form persist <ref>Evolution.berkeley.edu, (2014). The "bad" gene. [online] Available at: http://evolution.berkeley.edu/evolibrary/article/misconcep_04 [Last accessed on 22 November 2014]</ref>.<br> | ||
=== Examples === | |||
For examples see:<br> | |||
*[[Sickle cell anaemia|Sickle Cell anaemia ]] | |||
*[[Cystic Fibrosis|Cystic fibrosis ]][[Sickle cell anaemia|Sickle_cell_anaemia]]<br> | |||
=== References === | |||
= References = | |||
<references /> | <references /> | ||
Latest revision as of 06:23, 23 November 2014
Introduction
A heterozygous advantage is where carrying just one autosomal recessive mutant allele could provide a selective advantage to the individual, by providing protection from a disease, for example. This can explain why alleles which are lethal or deletarious in the homozygous form persist [1].
Examples
For examples see:
References
- ↑ Evolution.berkeley.edu, (2014). The "bad" gene. [online] Available at: http://evolution.berkeley.edu/evolibrary/article/misconcep_04 [Last accessed on 22 November 2014]