1,4 glycosidic bond

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Glycosidic bonds are formed due to a condensation reaction between two monosaccharides to form a polysaccharide. A condensation reaction is when two molecules combine to create a simple molecule andwater is eliminated.

The 1,4 glycosidic bond is formed between the carbon- 1 of one monosaccharide and carbon-4 of the other. There are are two types- 1,4 alpha and 1,4 beta glycosidic bonds. 1,4 alpha glycosidic bonds are formed when the OH on the carbon- 1 is below the glucose ring; while 1,4 beta glycosidic bonds are formed when the OH is above the plane[1][2].


  1. Jeremy M. Berg, John L. Tymoczko, Lubert Stryer . Biochemistry Seventh Edition Freeman
  2. http://dictionary.reference.com/browse/Condensation_reaction - 29/11/2013

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