1,4 glycosidic bond

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Alpha and Beta Glycosidic Bonds.png
Glycosidic bonds are formed due to condensation reactions between two monosaccharides (monomers is the general name), to form a polysaccharide (polymers, or many units of sugars). A condensation reaction is when two molecules join together to create a simple molecule and water is eliminated. The glycosidic bond can be hydrolysed by the addition of a water molecule to reform two monosaccharides (monomers, or single units of sugars). The 1,4 glycosidic bond is formed between the carbon-1 of one monosaccharide and carbon-4 of the other monosaccharide. There are are two types of glycosidic bonds - 1,4 alpha and 1,4 beta glycosidic bonds. 1,4 alpha glycosidic bonds are formed when the OH on the carbon-1 is below the glucose ring; while 1,4 beta glycosidic bonds are formed when the OH is above the plane[1]. When two alpha D-glucose molecules join together a more commonly occurring isomer of glucose compared to the L-glucose, form a glycosidic linkage, the term is known as a α-1,4-glycosidic bond[2].
=== References ===
  1. Jeremy M. Berg, John L. Tymoczko, Lubert Stryer . Biochemistry Seventh Edition Freeman
  2. Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Section 11.2, Complex Carbohydrates Are Formed by Linkage of Monosaccharides. Available from: http://www.ncbi.nlm.nih.gov/books/NBK22396/
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