1-6 glycosidic bond

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An α-1,6-[[Glycosidic bond|glycosidic bond]] is a [[Covalent|covalent]] bond formed between the -OH group on [[Carbon|carbon]] 1 of one [[Sugar|sugar]] and the -OH group on [[Carbon|carbon]] 6 of another sugar. This linkage causes branching&nbsp;within the [[Polysaccharide|polyscaccharide]]&nbsp;<ref>Stryer, L. (1988) Biochemistry. 3rd edn. New York: W. H. Freeman. 341-342</ref>.<sup>&nbsp;</sup>Formation of a [[Glycosidic bond|glycosidic bond]] is a [[Condensation Reaction|condensation]] reaction as a [[Molecule|molecule]] of [[Water|water]] is released, thus the bond can be broken by a molecule of [[Water|water]] in a [[Hydrolysis|hydrolysis]] reaction&nbsp;<ref>Bruce, A, Johnson, A, Lewis, J, Raff, M, Roberts, K and Walter, P. (2008). Molecular Biology of the Cell. 5th ed. New York: Garland Science. 56-57</ref>.&nbsp;α-1,6-[[Glycosidic bonds|glycosidic bonds]] can be found in [[Amylopectin|amylopectin]] and [[Glycogen|glycogen]] which are both [[Storage molecules|storage molecules]] composed of α-[[Glucose|glucose]]&nbsp;. Whilst most of the [[Glucose|glucose]] units in [[Amylopectin|amylopectin]] and [[Glycogen|glycogen]] are linked by [[1,4 glycosidic bonds|α-1,4- glycosidic bonds]], the branches are formed by α-1,6 glycosidic bonds, which occur around once every ten units in [[Glycogen|glycogen]] and once every thirty in [[Amylopectin|amylopectin]], thus, [[Glycogen|glycogen]] is more extensively branched&nbsp;<ref>Stryer, L. (1988) Biochemistry. 3rd edn. New York: W. H. Freeman. 341-342</ref>  
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An α-1,6-[[Glycosidic bond|glycosidic bond]] is a [[Covalent|covalent]] bond formed between the -OH group on [[Carbon|carbon]] 1 of one [[Sugar|sugar]] and the -OH group on [[Carbon|carbon]] 6 of another sugar. This linkage causes branching&nbsp;within the [[Polysaccharide|polyscaccharide]]&nbsp;<ref>Stryer, L. (1988) Biochemistry. 3rd edn. New York: W. H. Freeman. 341-342</ref>.<sup>&nbsp;</sup>Formation of a [[Glycosidic bond|glycosidic bond]] is a [[Condensation Reaction|condensation]] reaction as a [[Molecule|molecule]] of [[Water|water]] is released, thus the bond can be broken by a molecule of [[Water|water]] in a [[Hydrolysis|hydrolysis]] reaction&nbsp;<ref>Bruce, A, Johnson, A, Lewis, J, Raff, M, Roberts, K and Walter, P. (2008). Molecular Biology of the Cell. 5th ed. New York: Garland Science. 56-57</ref>.&nbsp;α-1,6-[[Glycosidic bonds|glycosidic bonds]] can be found in [[Amylopectin|amylopectin]] and [[Glycogen|glycogen]] which are both [[Storage molecules|storage molecules]] composed of α-[[Glucose|glucose]]&nbsp;. Whilst most of the [[Glucose|glucose]] units in [[Amylopectin|amylopectin]] and [[Glycogen|glycogen]] are linked by [[1,4 glycosidic bonds|α-1,4- glycosidic bonds]], the branches are formed by α-1,6 glycosidic bonds, which occur around once every ten units in [[Glycogen|glycogen]] and once every thirty in [[Amylopectin|amylopectin]], thus, [[Glycogen|glycogen]] is more extensively branched&nbsp;<ref>Stryer, L. (1988) Biochemistry. 3rd edn. New York: W. H. Freeman. 341-342</ref>
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http://www.bing.com/images/search?q=1%2c6+glycosidic+bond+image&view=detailv2&&id=948F3A6E88048A4A9929F2480D623B9DE73FBA1A&selectedIndex=0&ccid=vQz%2fIuDv&simid=608030897278422630&thid=OIP.Mbd0cff22e0ef459af96f8023ebca0a3ao0&ajaxhist=0
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This Image demonstrate an alpha 1,6 Glycosidic bond
  
 
=== References  ===
 
=== References  ===
  
 
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Revision as of 15:02, 22 October 2015

An α-1,6-glycosidic bond is a covalent bond formed between the -OH group on carbon 1 of one sugar and the -OH group on carbon 6 of another sugar. This linkage causes branching within the polyscaccharide [1]. Formation of a glycosidic bond is a condensation reaction as a molecule of water is released, thus the bond can be broken by a molecule of water in a hydrolysis reaction [2]. α-1,6-glycosidic bonds can be found in amylopectin and glycogen which are both storage molecules composed of α-glucose . Whilst most of the glucose units in amylopectin and glycogen are linked by α-1,4- glycosidic bonds, the branches are formed by α-1,6 glycosidic bonds, which occur around once every ten units in glycogen and once every thirty in amylopectin, thus, glycogen is more extensively branched [3]

http://www.bing.com/images/search?q=1%2c6+glycosidic+bond+image&view=detailv2&&id=948F3A6E88048A4A9929F2480D623B9DE73FBA1A&selectedIndex=0&ccid=vQz%2fIuDv&simid=608030897278422630&thid=OIP.Mbd0cff22e0ef459af96f8023ebca0a3ao0&ajaxhist=0

This Image demonstrate an alpha 1,6 Glycosidic bond

References

  1. Stryer, L. (1988) Biochemistry. 3rd edn. New York: W. H. Freeman. 341-342
  2. Bruce, A, Johnson, A, Lewis, J, Raff, M, Roberts, K and Walter, P. (2008). Molecular Biology of the Cell. 5th ed. New York: Garland Science. 56-57
  3. Stryer, L. (1988) Biochemistry. 3rd edn. New York: W. H. Freeman. 341-342
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