From The School of Biomedical Sciences Wikienzyme, which is best known for the (reversible) conversion of ethanol to acetylaldehyde (or ethanol) in the liver in humans. There are other ADH that catalyse the conversion of other alcohols to ketones and aldehydes. ADH is found in many organisms since ethanol is a rather ubiquitous molecule, as it is produced during fermentation. Depending on the ADH, either the forward reaction or the reverse reaction may be favoured. It is a dimeric enzyme with a turnover of 1200 molecules per second, and can use NAD+ or NADP+. The ADH in yeast, which was the first discovered, is far larger and more effective than the ADH in animals.
- ↑ Stamp S fastbleep (2014) [online] available at http://www.fastbleep.com/biology-notes/40/116/1196 accessed on: 26th November 2014.