Amino acid acceptor stem

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The Amino acid acceptor stem is the part on a tRNA molecule where the Amino Acid will bind. In order for the correct Amino acid to be brought to the right tRNA molecule, there is a process known as recognition and attachment that takes place. In order to do this, the tRNA molecule uses enzymes known as aminoacyl-tRNA synthetases and these bind the correct amino acid to the correct tRNA molecule via covalent bonds. As there are twenty different amino acids, there is often a different synthetase for each amino acid. However bacteria often use a lesser number of tRNA synthetases because they place the same amino acid on more than one tRNA. The amino acid that has bound to the correct tRNA (as identified by it’s anticodon) will be left unchanged, and the amino acid that has bound to the incorrect tRNA will be modified by another enzyme<ref>Alberts, B. et al. (2007) Molecular Biology of the Cell. Fifth Edition, United States: Garland Publishing Inc.</ref>. (Alberts et al., 2007: 370)  
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The [https://teaching.ncl.ac.uk/bms/wiki/index.php/Amino_acids amino acid] acceptor stem is the part on a [https://teaching.ncl.ac.uk/bms/wiki/index.php/TRNA tRNA] molecule where the Amino Acid will bind. In order for the correct Amino acid to be brought to the right tRNA molecule, there is a process known as recognition and attachment that takes place. In order to do this, the tRNA molecule uses enzymes known as aminoacyl-tRNA synthetases and these bind the correct amino acid to the correct tRNA molecule via [https://teaching.ncl.ac.uk/bms/wiki/index.php/Covalent_Bonds covalent bonds]. As there are twenty different amino acids, there is often a different synthetase for each amino acid. However bacteria often use a lesser number of tRNA synthetases because they place the same amino acid on more than one tRNA. The amino acid that has bound to the correct tRNA (as identified by it’s anticodon) will be left unchanged, and the amino acid that has bound to the incorrect tRNA will be modified by another enzyme<ref>Alberts, B. et al. (2007) Molecular Biology of the Cell. Fifth Edition, United States: Garland Publishing Inc.</ref>. (Alberts et al., 2007: 370)  
  
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Revision as of 19:44, 20 November 2014

The amino acid acceptor stem is the part on a tRNA molecule where the Amino Acid will bind. In order for the correct Amino acid to be brought to the right tRNA molecule, there is a process known as recognition and attachment that takes place. In order to do this, the tRNA molecule uses enzymes known as aminoacyl-tRNA synthetases and these bind the correct amino acid to the correct tRNA molecule via covalent bonds. As there are twenty different amino acids, there is often a different synthetase for each amino acid. However bacteria often use a lesser number of tRNA synthetases because they place the same amino acid on more than one tRNA. The amino acid that has bound to the correct tRNA (as identified by it’s anticodon) will be left unchanged, and the amino acid that has bound to the incorrect tRNA will be modified by another enzyme[1]. (Alberts et al., 2007: 370)

References

  1. Alberts, B. et al. (2007) Molecular Biology of the Cell. Fifth Edition, United States: Garland Publishing Inc.
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