This is the stage of mitosis and meiosis where genetic information is moved to opposite sides of the dividing cell. In mitosis, with spindles joined to centromeres and the sister chromatids lined up on the metaphase plate, one chromatid is pulled to either side of the cell. There are two stages of anaphase in mitosis; anaphase A, where chromosomes move to the poles and then anaphase B, where the poles move apart. Anaphase occurs twice in meiosis (Anaphase 1 and 2). Anaphase 1 involes the separation of the each pair of sister chromatids to opposite sides of the cell. Anaphase 2, similarly to mitosis involes the actual splitting of sister chromatids to single chromatids.