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Antidepressants are a family of drugs used to treat a wide range of depressions, which can be relatively low and hence easily controlled through mild mediation, or extremely severe leading to a deterioration in health potentially culminating in premature death [1].

Antidepressants can elevate and reduce the mood of the patient depending on their type and severity of depression. Tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOI) are common drugs used to raise the mood of the patients, whereas reserpine, alpha-Methyltryrosine and methyldopa are used to lower the mood of manic patients [1].

TCAs and MAOIs trigger an increase in noradrenaline and serotonin in the brain [1] .

An example of an antidepressant is Cipramil.

SSRIs are another class of antidepressants which are relatively new. [2] An example of an SSRI is Fluoxetine (Prozac).


  1. 1.0 1.1 1.2 Rang et al. 2007, Rang and dale's Pharmacology, 6th edition, Philadelphia: Elsevier Limited, 537-562
  2. ID: CD001851 AU: Geddes, JR AU: Freemantle, N AU: Mason, J AU: Eccles, MP AU: Boynton, J TI: Selective serotonin reuptake inhibitors (SSRIs) versus other antidepressants for depression SO: The Cochrane Database of Systematic Reviews YR: 1999 NO: 4 PB: John Wiley & Sons, Ltd KY: Antidepressive Agents [therapeutic use];Depressive Disorder [drug therapy];Serotonin Uptake Inhibitors [therapeutic use];Humans[checkword] CC: DEPRESSN DOI: 10.1002/14651858.CD001851 US:
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