Autophosphorylation takes place in an enzyme-linked receptor called a Receptor Tyrosine Kinase (RTK). When the external domain of the receptor comes into contact with a signal it dimerises. This then triggers lots of phosphates to bind to the intracellular domain of the Receptor providing a docking site for other proteins. This is autophosphorylation.
- ↑ Enzyme-Linked Receptors, http://www.fastbleep.com/biology-notes/31/174/1000, accessed on 22/11/13