Bacterial chromosome replication

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The majority of bacterial chromosomes are circular in composition. Replication of these cirular bacterial chromosomes is initiated at a unique site in the [https://teaching.ncl.ac.uk/bms/wiki/index.php/DNA DNA] called the "Origin of Replication" or "OriC". Replication proceeds from this point bi-directionally from the origin (OriC) to the terminus referred to as "TerC". There are, therefore, two sites of DNA synthesis at structures called replication forks. 
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The majority of bacterial [https://teaching.ncl.ac.uk/bms/wiki/index.php/Chromosome chromosomes] are circular in composition. Replication of these cirular bacterial chromosomes is initiated at a unique site in the [https://teaching.ncl.ac.uk/bms/wiki/index.php/DNA DNA] called the "Origin of Replication" or "[https://teaching.ncl.ac.uk/bms/wiki/index.php/OriC OriC]". [https://teaching.ncl.ac.uk/bms/wiki/index.php/Dna_replication Replication] proceeds from this point bi-directionally from the origin (OriC) to the terminus referred to as "TerC". There are, therefore, two sites of DNA synthesis at structures called replication forks. 
  
. [[Image:07-06_BidirectionalRep_L.jpg|right|600x300px|Replication of a circular bacterial chromosome]]
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[[Image:07-06 BidirectionalRep L.jpg|right|600x300px|Replication of a circular bacterial chromosome]]
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===== . References:<br> =====
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*Jon M Kaguni, DnaA: Controlling the Initiation of Bacterial DNA Replication and More. Annu. Rev. Microbiol. 2006. 60: 351-71
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*Alberts B, Johnson A, Lewis J et al. Molecular Biology of the Cell 4th Edition. 2002. New York, Garland Science.&nbsp;

Revision as of 17:28, 16 November 2014

The majority of bacterial chromosomes are circular in composition. Replication of these cirular bacterial chromosomes is initiated at a unique site in the DNA called the "Origin of Replication" or "OriC". Replication proceeds from this point bi-directionally from the origin (OriC) to the terminus referred to as "TerC". There are, therefore, two sites of DNA synthesis at structures called replication forks. 



Replication of a circular bacterial chromosome
. References:
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