Bacterial chromosome replication

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The majority of bacterial chromosomes are circular in composition. Replication of these cirular bacterial chromosomes is initiated at a unique site in the [https://teaching.ncl.ac.uk/bms/wiki/index.php/DNA DNA] called the "Origin of Replication" or "OriC". Replication proceeds from this point bi-directionally from the origin (OriC) to the terminus referred to as "TerC". There are, therefore, two sites of DNA synthesis at structures called replication forks. 
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The majority of bacterial [[Chromosome|chromosomes]] are circular in composition. Replication of these circular bacterial chromosomes is initiated at a unique site in the DNA called the "[[Origin of Replication|Origin of Replication]]" or "OriC". Replication proceeds from this point bi-directionally from the origin (OriC) to the terminus referred to as "TerC". There are, therefore, two sites of [[DNA synthesis|DNA synthesis]] at structures called [[replication forks|replication forks]] <ref>Alberts B, Johnson A, Lewis J et al. Molecular Biology of the Cell 4th Edition. 2002. New York, Garland Science.</ref><ref>Jon M Kaguni, DnaA: Controlling the Initiation of Bacterial DNA Replication and More. Annu. Rev. Microbiol. 2006. 60: 351-71</ref>.&nbsp;  
  
.&nbsp;[[Image:07-06_BidirectionalRep_L.jpg|right|600x300px|Replication of a circular bacterial chromosome]]
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=== Refereneces<br> ===
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<references />

Latest revision as of 10:28, 17 November 2014

The majority of bacterial chromosomes are circular in composition. Replication of these circular bacterial chromosomes is initiated at a unique site in the DNA called the "Origin of Replication" or "OriC". Replication proceeds from this point bi-directionally from the origin (OriC) to the terminus referred to as "TerC". There are, therefore, two sites of DNA synthesis at structures called replication forks [1][2]

Refereneces

  1. Alberts B, Johnson A, Lewis J et al. Molecular Biology of the Cell 4th Edition. 2002. New York, Garland Science.
  2. Jon M Kaguni, DnaA: Controlling the Initiation of Bacterial DNA Replication and More. Annu. Rev. Microbiol. 2006. 60: 351-71
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