Barr bodies

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A barr body<ref>''Barr body'' http://en.wikipedia.org/wiki/Barr_body September 3, 2014.</ref> is an inactive [[X chromosome|X chromosome]] in female cells&nbsp;or the inactive Z in a male. [[Lyonization|Lyonization]] is the process where the chromosome is inactivated in species. In addition to this, it is thought to be down to complete chance as to which X chromosome is inactivated and it is still unknown to this day as to how the cell decide which X chromosome is to be made into a Barr body.
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A barr body<ref>''Barr body'' http://en.wikipedia.org/wiki/Barr_body September 3, 2014.</ref> is an inactive [[X chromosome|X chromosome]] in female cells&nbsp;or the inactive Z in a male. [[Lyonization|Lyonization]] is the process where the chromosome is inactivated in species. In addition to this, it is thought to be down to complete chance as to which X chromosome is inactivated and it is still unknown to till date&nbsp;as to how the cell decides which X chromosome is to be made into a Barr body.  
  
 
In men and women with more than one X chromosome, the number of Barr bodies visible at interphase is always one less than the total number of X chromosomes.  
 
In men and women with more than one X chromosome, the number of Barr bodies visible at interphase is always one less than the total number of X chromosomes.  
  
For example, a man with [[Klinefelter syndrome|Klinefelters syndrome]], with 47 chromosomes, XXY [[Karyotype|karyotype]] have two Barr bodies, whereas an female with [[Turner syndrome|Turners syndrome]], with 45 chromosomes, XO karyotype does not have any Barr bodies<ref>Sloane.E, The Biology of Women, 4th Edition, Cengage Learning, 2002, pages 133</ref>.<br>  
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For example, a&nbsp;person with [[Klinefelter syndrome|Klinefelters syndrome]], which is characterized by&nbsp;47 chromosomes and XXY [[Karyotype|karyotype]]&nbsp;will have two Barr bodies, whereas an individual&nbsp;with [[Turner syndrome|Turners syndrome]]&nbsp;has 45 chromosomes and&nbsp;karyotype XO&nbsp;does not have any Barr bodies<ref>Sloane.E, The Biology of Women, 4th Edition, Cengage Learning, 2002, pages 133</ref>.<br>
  
 
=== References<br> ===
 
=== References<br> ===
  
 
<references />
 
<references />

Revision as of 16:58, 2 December 2015

A barr body[1] is an inactive X chromosome in female cells or the inactive Z in a male. Lyonization is the process where the chromosome is inactivated in species. In addition to this, it is thought to be down to complete chance as to which X chromosome is inactivated and it is still unknown to till date as to how the cell decides which X chromosome is to be made into a Barr body.

In men and women with more than one X chromosome, the number of Barr bodies visible at interphase is always one less than the total number of X chromosomes.

For example, a person with Klinefelters syndrome, which is characterized by 47 chromosomes and XXY karyotype will have two Barr bodies, whereas an individual with Turners syndrome has 45 chromosomes and karyotype XO does not have any Barr bodies[2].

References

  1. Barr body http://en.wikipedia.org/wiki/Barr_body September 3, 2014.
  2. Sloane.E, The Biology of Women, 4th Edition, Cengage Learning, 2002, pages 133
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