Bronchoconstriction

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Bronchoconstriction is the constriction of airways in the lungs, caused by smooth muscle contraction in the lungs decreasing their diameter. Both the [https://teaching.ncl.ac.uk/bms/wiki/index.php/Autonomic_Nervous_System autonomic nervous system] and chemical mediators are responsible for regulating this process<ref name="larson">larson</ref>.  
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Bronchoconstriction is the constriction of airways in the [[lungs|lungs]], caused by [[smooth muscle contraction|smooth muscle contraction]] in the lungs decreasing their diameter. Both the [[autonomic nervous system|autonomic nervous system]] and chemical mediators are responsible for regulating this process<ref>Larson Jr, Jaffe, Practical Anaesthetic Management, The Art of Anaesthesiology, 1st Edition, Springer International Publishing, 2017, 52 - 53</ref>.  
  
There are drugs that can cause bronchoconstriction such as: muscarinic agonists (e.g. pilocarpine), β2 noradrenergic receptor antagonists (e.g. propranolol), A1 noradrenergic receptor antagonists (e.g. prazosin) and H1 agonists (e.g. histamine).  
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There are drugs that can cause bronchoconstriction such as: [[muscarinic agonists|muscarinic agonists]] (e.g. [[pilocarpine|pilocarpine]]), [[β2 noradrenergic receptor antagonists|β2 noradrenergic receptor antagonists]] (e.g. [[propranolol|propranolol]]), [[A1 noradrenergic receptor antagonists|A1 noradrenergic receptor antagonists]] (e.g. [[prazosin|prazosin]]) and [[H1 agonists|H1 agonists]] (e.g. [[histamine|histamine]]).  
  
[https://teaching.ncl.ac.uk/bms/wiki/index.php/Asthma Asthma], a common ailment in which airways become irritated and bronchoconstriction causes difficulty breathing, is treated by drugs that inhibit bronchoconstriction and allow [https://teaching.ncl.ac.uk/bms/wiki/index.php/Bronchodilation bronchodilation] to occur.  
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[[Asthma|Asthma]], a common ailment in which airways become irritated and bronchoconstriction causes difficulty breathing, is treated by drugs that inhibit bronchoconstriction and allow [[bronchodilation|bronchodilation]] to occur.  
  
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=== References ===
  
= '''References'''  =
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<references />
 
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1. Larson Jr, Jaffe, Practical Anaesthetic Management, The Art of Anaesthesiology, 1st Edition, Springer International Publishing, 2017, 52 - 53
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Latest revision as of 16:57, 23 October 2018

Bronchoconstriction is the constriction of airways in the lungs, caused by smooth muscle contraction in the lungs decreasing their diameter. Both the autonomic nervous system and chemical mediators are responsible for regulating this process[1].

There are drugs that can cause bronchoconstriction such as: muscarinic agonists (e.g. pilocarpine), β2 noradrenergic receptor antagonists (e.g. propranolol), A1 noradrenergic receptor antagonists (e.g. prazosin) and H1 agonists (e.g. histamine).

Asthma, a common ailment in which airways become irritated and bronchoconstriction causes difficulty breathing, is treated by drugs that inhibit bronchoconstriction and allow bronchodilation to occur.

References

  1. Larson Jr, Jaffe, Practical Anaesthetic Management, The Art of Anaesthesiology, 1st Edition, Springer International Publishing, 2017, 52 - 53
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