Cyclic AMP (cAMP) or cyclic adenosine monophosphate acts as a secondary messenger and is used in cell signalling. It can be deactivated by phosphodiesterase (PDE) into AMP. cAMP can activate protein kinase A (PKA) by binding to it's regulatory subunits which activates and release the catalytic subunits. These active catalytic subunits can then go on to phosphorylate other proteins, creating a signalling cascade. ATP is converted to cAMP by adenylyl cyclase, cAMP is then used in a range of signalling pathways.
- ↑ Alberts Moleucular Biology of the cell 5th edition - page 895