Cell Communication

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(Created page with "Cell communication Plasma membrane acts as a barrierof the cell to control the passage of substances in and out of the cells, therefore, it allows the communication between cell...")
 
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Cell communication
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<span style="line-height: 1.5em;">Different types of extracellular signal allows cell to respond differently. The signal [[Molecule|molecule]] acts as the primary messenger, bind with the [[Membrane receptor|membrane receptor]], causing variation of cellular responds.</span>
  
Plasma membrane acts as a barrierof the cell to control the passage of substances in and out of the cells, therefore, it allows the communication between cells and cell to the
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However, same types of signal molecule, sometimes, bind with differents receptors, triggers different responds. For example:
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=== Nicotinic Ach receptor<br>  ===
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It is a kind of [[Ion-channel-coupled receptor|ion-channel linked receptor]]. As the [[Neurotransmitter|neurotransmitter]] [[Nicotinic Ach receptor|Ach]] binds to the receptor, it allows the [[Sodium|sodium]] ions to pass through the channel. Consequently, neuronal membrane is depolarised and [[Muscle contraction|muscle contraction]] occurs.<br>
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=== Muscarinic Ach receptor  ===
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It is a type of [[G-protein Coupled Receptor|G-protein linked receptor]] where Ach binds on the surface of the receptor. This activates the alpha subunits of [[Heterotrimeric G-proteins|G protein]], causing the release of [[GDP|GDP]], and binding with [[GTP|GTP]]. The secondary messenger triggers the potassium ion channel to open, K<sup>+</sup> ions flow from the cell to the [[Extracellular matrix|extracellular matrix]]. This results in membrane hyperpolarisation. Hence, the membrane will return back to its resting state<ref>Hardin, Bertoni,Kleinsmith 2010. Becker's World of the Cell Eighth Edition.p386</ref>.<br>
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=== Reference  ===
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<references /><br>

Latest revision as of 23:07, 16 November 2018

Different types of extracellular signal allows cell to respond differently. The signal molecule acts as the primary messenger, bind with the membrane receptor, causing variation of cellular responds.

However, same types of signal molecule, sometimes, bind with differents receptors, triggers different responds. For example:

Nicotinic Ach receptor

It is a kind of ion-channel linked receptor. As the neurotransmitter Ach binds to the receptor, it allows the sodium ions to pass through the channel. Consequently, neuronal membrane is depolarised and muscle contraction occurs.

Muscarinic Ach receptor

It is a type of G-protein linked receptor where Ach binds on the surface of the receptor. This activates the alpha subunits of G protein, causing the release of GDP, and binding with GTP. The secondary messenger triggers the potassium ion channel to open, K+ ions flow from the cell to the extracellular matrix. This results in membrane hyperpolarisation. Hence, the membrane will return back to its resting state[1].

Reference

  1. Hardin, Bertoni,Kleinsmith 2010. Becker's World of the Cell Eighth Edition.p386

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