Centrosome

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A centrosome is a region in the [[Cytoplasm|cytosplasm of]] a cell in close proximity to a [[Nucleus|nucleus]]&nbsp;<ref>Hartl et al. 2006, Essential Genetics p460, 4th edition : Jones and Bartlett Publishers</ref>. Within the centrosome are contained a pair of [[Centrioles|centrioles]] which play an essential role in the formation of the [[Mitoitic spindle|mitoitic spindle]] during replication of [[DNA|DNA]]&nbsp;(Deoxyribose Nucleic Acid).  
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A centrosome is a region in the [[Cytoplasm|cytoplasm]] of a cell which is in close proximity to a [[Nucleus|nucleus]]&nbsp;<ref>Hartl et al. 2006, Essential Genetics p460, 4th edition : Jones and Bartlett Publishers</ref>. The centrosome contains a pair of [[Centrioles|centrioles]] which play an essential role in the formation of the [[Mitoitic spindle|mitotic spindle]] during&nbsp;[[DNA_replication|DNA&nbsp;replication]].  
  
Every centrosome consists of [[Pericentriolar matrix|pericentriolar matrix]], which envelopes the [[Centrioles|centrioles]] found in the centrosome&nbsp;<ref name="null">Alberts et al. 2008, Molecular Biology of the Cell p1076, 5th edition, New York : Garland Science</ref>. From the matrix, an array of [[Microtubules|microtubules]] form the [[Mitotic spindle|mitotic spindle]] at the correct stage during [[Cell division|cell division]].  
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The inner region of the centrosome is called the&nbsp;[[Pericentriolar matrix|pericentriolar matrix]], which envelopes the [[Centrioles|centrioles]] found in the centrosome&nbsp;<ref name="null">Alberts et al. 2008, Molecular Biology of the Cell p1076, 5th edition, New York : Garland Science</ref>. From the matrix, an array of [[Microtubules|microtubules]] form the [[Mitotic spindle|mitotic spindle]] at the correct stage during [[Cell division|cell division]].  
  
In the majority of [[Eukaryotic|eukaryotic]] cells, duplication of the centrosome starts in the later stages of [[G1|G1]] and is completed during the systhesis stages of [[Mitosis|mitosis]]&nbsp;<ref>Hartl et al. 2006, Essential Genetics p460, 4th edition : Jones and Bartlett Publishers</ref>.  
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In the majority of [[Eukaryotic|eukaryotic]] cells, duplication of the centrosome starts in the later stages of [[G1|G1]] and is completed during the synthesis stages of [[Mitosis|mitosis]]&nbsp;<ref>Hartl et al. 2006, Essential Genetics p460, 4th edition : Jones and Bartlett Publishers</ref>.  
  
 
=== References  ===
 
=== References  ===
  
 
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Revision as of 15:40, 30 November 2012

A centrosome is a region in the cytoplasm of a cell which is in close proximity to a nucleus [1]. The centrosome contains a pair of centrioles which play an essential role in the formation of the mitotic spindle during DNA replication.

The inner region of the centrosome is called the pericentriolar matrix, which envelopes the centrioles found in the centrosome [2]. From the matrix, an array of microtubules form the mitotic spindle at the correct stage during cell division.

In the majority of eukaryotic cells, duplication of the centrosome starts in the later stages of G1 and is completed during the synthesis stages of mitosis [3].

References

  1. Hartl et al. 2006, Essential Genetics p460, 4th edition : Jones and Bartlett Publishers
  2. Alberts et al. 2008, Molecular Biology of the Cell p1076, 5th edition, New York : Garland Science
  3. Hartl et al. 2006, Essential Genetics p460, 4th edition : Jones and Bartlett Publishers
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