Chromosome 13 is one of 22 autosomal pairs of chromosomes found in humans. It is thought to contain about 114 million base pairs and codes for between 600 and 700 genes which code for various things from ATPase to specific diseases. It is widely associated breast cancer; gene BRCA2 and some bladder cancers as well as Wilson's disease which is a mutation of the ATP7B gene.
There are also many chromosomal conditions associated with chromosome 13 including Patau syndrome which is trisomy of chromosome 13 and Retinoblastoma which can be caused by deletion of a specific region (13q14) containing the RB1 gene .
- ↑ Genetics Home Reference (2012) 'chromosome 13' http://ghr.nlm.nih.gov/chromosome/13#resources
- ↑ Atlas Genetics Oncology (2012) 'chromosome 13' http://atlasgeneticsoncology.org/Indexbychrom/idxa_13.html