Co-enzyme

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A coenzyme is a molecule which helps the functioning and activity of an enzyme by binding and therefore activating it to form the holoenzyme[1]. Coenzymes are nonpolypeptide small molecules or ions that are bound in the active site, and can be chemically modified during the reaction so need to be replaced or regenerated afterwards[2]. Examples include NAD+ (nicotinamide adenine dinucleotide), FAD (flavin adenine dinucleotide) and haem groups that bind oxygen in haemoglobin[3].

References

  1. Medicine Net, Coenzymes, https://www.medicinenet.com/script/main/art.asp?articlekey=13153
  2. Lodish H, Kaiser CA, Bretcher A, Amon A, Berk A, Kneger M, Ploegh H, Scott MP. Molecular Cell Biology. 7th Ed, New York: W.H. Freeman and Company. 2013.
  3. Lodish H, Kaiser CA, Bretcher A, Amon A, Berk A, Kneger M, Ploegh H, Scott MP. Molecular Cell Biology. 7th Ed, New York: W.H. Freeman and Company. 2013.
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