Codon

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Also&nbsp;known as&nbsp;[[Trinucleotide|trinucleotides]]. A&nbsp;codon is made up of&nbsp;three [[Nucleotide|nucleotides]] found in [[DNA|DNA]] or [[MRNA|mRNA]], and codes for one specific [[Amino acid|amino acid]].&nbsp;The order of these three nucleotides is&nbsp;unique&nbsp;and vitally important in the coding of&nbsp;its [[Amino acid|amino acid]]&nbsp;<ref>ALBERTS, B. et al. (2008) Molecular Biology Of The Cell. 5th edition. New York: Garland Science.</ref>.  
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Also&nbsp;known as&nbsp;[[Trinucleotide|trinucleotides]]. A&nbsp;codon is made up of&nbsp;three adjacent&nbsp;[[Nucleotide|nucleotides]] found in [[DNA|DNA]] or [[MRNA|mRNA]], and codes for one specific [[Amino acid|amino acid]].&nbsp;The order of these three nucleotides is&nbsp;unique&nbsp;and vitally important in the coding of&nbsp;its [[Amino acid|amino acid]]&nbsp;<ref>ALBERTS, B. et al. (2008) Molecular Biology Of The Cell. 5th edition. New York: Garland Science.</ref>.  
  
In some instances, there&nbsp;can be&nbsp;more than one codon which corresponds to the same [[Amino acid|amino acid]]&nbsp;<ref>Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon Anton A. Turanov, Alexey V. Lobanov, Dmitri E. Fomenko, Hilary G. Morrison, Mitchell L. Sogin, Lawrence A. Klobutcher, Dolph L. Hatfield, and Vadim N. Gladyshev (9 January 2009) Science 323 (5911), 259. [DOI: 10.1126/science.1164748] One codon can code for two different amino acids within the same gene, with the choice determined by an RNA structure in an untranslated region.</ref>. This is why the codon code goes by the term degenerate.
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In some instances, there&nbsp;can be&nbsp;more than one codon which corresponds to the same [[Amino acid|amino acid]]&nbsp;<ref>Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon Anton A. Turanov, Alexey V. Lobanov, Dmitri E. Fomenko, Hilary G. Morrison, Mitchell L. Sogin, Lawrence A. Klobutcher, Dolph L. Hatfield, and Vadim N. Gladyshev (9 January 2009) Science 323 (5911), 259. [DOI: 10.1126/science.1164748] One codon can code for two different amino acids within the same gene, with the choice determined by an RNA structure in an untranslated region.</ref>.  
  
=== References ===
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For example, both UUC and UUU code for Phenylalanine.
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This is why the codon code goes by the term degenerate.
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Codons having complementary bases to a particular anticodon of a tRNA molecule carrying amino acids.<ref>ALBERTS, B. et al. (2008) Molecular Biology Of The Cell. 5th edition. New York: Garland Science</ref>
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This base-pairing process creates specificity of amino acids for protein synthesis.
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References  
  
 
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Revision as of 14:11, 17 October 2014

Also known as trinucleotides. A codon is made up of three adjacent nucleotides found in DNA or mRNA, and codes for one specific amino acid. The order of these three nucleotides is unique and vitally important in the coding of its amino acid [1].

In some instances, there can be more than one codon which corresponds to the same amino acid [2].

For example, both UUC and UUU code for Phenylalanine.

This is why the codon code goes by the term degenerate.


Codons having complementary bases to a particular anticodon of a tRNA molecule carrying amino acids.[3]

This base-pairing process creates specificity of amino acids for protein synthesis.




References

  1. ALBERTS, B. et al. (2008) Molecular Biology Of The Cell. 5th edition. New York: Garland Science.
  2. Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon Anton A. Turanov, Alexey V. Lobanov, Dmitri E. Fomenko, Hilary G. Morrison, Mitchell L. Sogin, Lawrence A. Klobutcher, Dolph L. Hatfield, and Vadim N. Gladyshev (9 January 2009) Science 323 (5911), 259. [DOI: 10.1126/science.1164748] One codon can code for two different amino acids within the same gene, with the choice determined by an RNA structure in an untranslated region.
  3. ALBERTS, B. et al. (2008) Molecular Biology Of The Cell. 5th edition. New York: Garland Science



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