Crohn's disease is one form of an inflammatory bowel disease (IBD). It is a disease in which the immune system attacks the microbiota of the gut, causing inflammation. The exact cause of the disease is not fully understood, but it is believed to be linked to both genetic and environmental factors. Crohn's disease can affect any part of the GI tract but the most common symptoms are chronic diarrhoea, abdominal pain and blood and mucus in the stools.
As it is a chronic condition, the aim of most treatment is to reach and maintain a state of remision - that is to express a reduced set of symptons, or none at all, over a period of time.
- ↑ Murphy K, Weaver C. Janeway's Immunobiology.9th Edition. Garland Science, Taylor and Francis Group. New York and London. 2016.
- ↑ US Department of Health and Human Services. Crohn's Disease. 2017 [cited from 22.10.17]. Available from: https://rarediseases.info.nih.gov/diseases/10232/crohns-disease
- ↑ Ha, Francis, and Hanan Khalil. “Crohn’s Disease: A Clinical Update.” Therapeutic Advances in Gastroenterology 8.6 (2015): 352–359.
- ↑ Crohn’s and Colitis. (2018). Learn About Treatment Options for Crohn’s Disease. [online] Available at: https://www.crohnsandcolitis.com/crohns/disease-treatment [Accessed 20 Oct. 2018].