Danio rerio

From The School of Biomedical Sciences Wiki
Jump to: navigation, search

Danio rerio, also known as Zebrafish, are a type of ray-finned bony fish that are used as a model eukaryotic organism for genetic analysis. Reasons why they're used so widely include: the fact that they're small and robust, cheap to maintain, have a short generation time, produce lots of offsrping at once, have a fast development rate to maturity and have a similair genetic structure to humans (share 70% of genes)[1]. Due to their genetic similarity to humans, zebrafish can be used to carry out Gene knockout's. This is useful when investigating which mutations may lead to specific symptons in genetic diseases.

In particular, zebrafish are valuable in the study of early development as they produce transparent embryos. This allows scientists to observe physiological changes as well as any fluorescent markers genetic markers in transgenic embryos[2]. These specific characteristics of zebrafish make them good Model organism's.

References

  1. Why use the zebrafish in research?.Stories. 2014 [cited 5/12/18]; available from: https://www.yourgenome.org/facts/why-use-the-zebrafish-in-research
  2. Why use zebrafish to study human diseases? Intramural Research programme. Accessed: 06/12/18 https://irp.nih.gov/blog/post/2016/08/why-use-zebrafish-to-study-human-diseases


Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox