Denature

From The School of Biomedical Sciences Wiki
Revision as of 10:01, 22 October 2012 by Nnjm2 (Talk | contribs)
Jump to: navigation, search

When a protein is changed in shape and "unfolded", it is said to be denatured.  This can occur in a number of ways, from a change in environmental factors (i.e. high/low temperature) to the addition of different chemicals (i.e. solvents), causing breaking and changing of integral bonds within the protein.

Denaturing is particularly important to consider when studying enzymes- If a protein's active site is changed so that it is no longer complementary to it's substrate then it cannot carry out it's function correctly [1].

References

  1. Alberts, B. Johnson, A. Lewis, J. Raff, M. Roberts, K. Walter, P (2008). Molecular biology of the cell. 5th ed. New York: Garland Science. 130.


Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox