Disjunction

From The School of Biomedical Sciences Wiki
(Difference between revisions)
Jump to: navigation, search
 
(5 intermediate revisions by 3 users not shown)
Line 1: Line 1:
Disjunction is a process which sees [[Homologous chromosomes|homologous chromosomes]], that are lined up along the [[Equatorial plate|equatorial plate]], gradually drawn towards opposite poles of a [[Cell|cell]], by structures known as [[Spindle fibres|spindle fibres]]. The process of disjunction occurs in both mitosis and [[Meiosis|meiosis]] cell division and is associated with the [[Anaphase|anaphase]] stage. If two sister [[Chromatids|chromatids]] do not separate correctly during the process, nondisjunction occurs. This then leads to an incorrect number of chromosomes, in one of the two dividing cells, and this is known as [[Aneuploidy]].
+
Disjunction is a process which sees [[Homologous chromosomes|homologous chromosomes]], that are lined up along the [[Equatorial plate|equatorial plate]], gradually drawn towards opposite poles of a [[Cell|cell]], by structures known as [[Spindle fibres|spindle fibres]]. The process of disjunction occurs in both [[Mitosis|mitosis]] and [[Meiosis|meiosis]] cell division and is associated with the [[Anaphase|anaphase]] stage. If two sister [[Chromatids|chromatids]] do not separate correctly during the process, [[Nondisjunction]] occurs. This then leads to an incorrect number of [[Chromosome|chromosomes]], in one of the two dividing cells, and this is known as [[Aneuploidy]]. This can lead to disorders such as a trisomy 21 ([[Downs syndrome|Downs syndrome]]), trisomy 18 ([[Edwards syndrome|Edwards syndrome]]), trisomy 13 ([[Patau's Syndrome|Patau's Syndrome]]).

Latest revision as of 20:38, 6 December 2018

Disjunction is a process which sees homologous chromosomes, that are lined up along the equatorial plate, gradually drawn towards opposite poles of a cell, by structures known as spindle fibres. The process of disjunction occurs in both mitosis and meiosis cell division and is associated with the anaphase stage. If two sister chromatids do not separate correctly during the process, Nondisjunction occurs. This then leads to an incorrect number of chromosomes, in one of the two dividing cells, and this is known as Aneuploidy. This can lead to disorders such as a trisomy 21 (Downs syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau's Syndrome).

Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox