Fibronectin

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 Fibronectin is an [[Extracellular matrix|extracellular matrix]] protein that helps cells attach to the matrix by acting as a "linker" that binds to a cell-surface [[Integrin|integrin]] molecule on one end and to a matrix component (such as collagen) on the other end.
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Fibronectin is an [[Extracellular matrix|extracellular matrix]] protein that helps cells attach to the [[Matrix|matrix]] by acting as a "linker" that binds to a cell-surface [[Integrin|integrin]] molecule on one end and to a matrix component (such as collagen) on the other end<ref>Alberts, Bray, Hopkin, Johnson, Lewis, Raff, Roberts, Walter 2014, Essential Cell Biology, 4th edn, Garland Science, New York.</ref>. Fibronectin proteins are composed of a linear arrangement of repeating stuctural molecules that are classed into domains referred to as fibronectin repeats. The exact order of these repeats varies due to alternative splicing<ref>Cassimeris L, Lingappa VR, Plopper G. Lewin's Cells. 2nd Ed, Sudbury:Jones and Bartlett. 2011</ref>.  
  
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=== References  ===
  
 
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<references />
&nbsp; <references /> Alberts, Bray, Hopkin, Johnson, Lewis, Raff, Roberts, Walter 2014, Essential Cell Biology, 4th edn, Garland Science, New York.
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Latest revision as of 16:11, 16 November 2018

Fibronectin is an extracellular matrix protein that helps cells attach to the matrix by acting as a "linker" that binds to a cell-surface integrin molecule on one end and to a matrix component (such as collagen) on the other end[1]. Fibronectin proteins are composed of a linear arrangement of repeating stuctural molecules that are classed into domains referred to as fibronectin repeats. The exact order of these repeats varies due to alternative splicing[2].

References

  1. Alberts, Bray, Hopkin, Johnson, Lewis, Raff, Roberts, Walter 2014, Essential Cell Biology, 4th edn, Garland Science, New York.
  2. Cassimeris L, Lingappa VR, Plopper G. Lewin's Cells. 2nd Ed, Sudbury:Jones and Bartlett. 2011
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