Gene knockout

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(Good edit. Cleaned it up a bit. Added a reference section.)
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&nbsp;A gene knockout is a [[Deletion_mutation|deletion mutation ]]where part of a [[Gene|gene]] is missing, making the [[Wild_-_type|wildtype]] nonfunctional. Gene knockout is a technique often used when producing [[Transgenic_Organism|transgenic]] animals to study the function of specific [[Gene|genes]], as loss of a certian funtion in the [[Transgenic_Organism|transgenic]] animal can give important information about the function of the [[Gene|gene]] that has been knocked out. Gene knockout is also often used to produce transgenic mice with knockouts of [[Homologous|homologs]] of [[Gene|genes]] associated with human disease that act as models for humans diseases<ref>D.L. Hartl. M. Ruvolo. Genetics: Analysis of Genes and Genomes. Jones and Bartlett learning. 2012.</ref>. == References == <references></references>
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A gene knockout is a [[deletion mutation|deletion mutation]] where part of a [[Gene|gene]] is missing, making the [[Wild - type|wildtype]] nonfunctional. Gene knockout is a technique often used when producing [[Transgenic Organism|transgenic]] animals to study the function of specific [[Gene|genes]], as loss of a certian funtion in the [[Transgenic Organism|transgenic]] animal can give important information about the function of the [[Gene|gene]] that has been knocked out. Gene knockout is also often used to produce [[transgenic mice|transgenic mice]] with knockouts of [[Homologous|homologs]] of [[Gene|genes]] associated with human disease that act as models for humans diseases<ref>D.L. Hartl. M. Ruvolo. Genetics: Analysis of Genes and Genomes. Jones and Bartlett learning. 2012.</ref>.  
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=== References ===
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<references />

Revision as of 14:50, 4 December 2016

A gene knockout is a deletion mutation where part of a gene is missing, making the wildtype nonfunctional. Gene knockout is a technique often used when producing transgenic animals to study the function of specific genes, as loss of a certian funtion in the transgenic animal can give important information about the function of the gene that has been knocked out. Gene knockout is also often used to produce transgenic mice with knockouts of homologs of genes associated with human disease that act as models for humans diseases[1].

References

  1. D.L. Hartl. M. Ruvolo. Genetics: Analysis of Genes and Genomes. Jones and Bartlett learning. 2012.
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