Glomerulus

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The glomerulus is the beginning section of the [[Nephron|nephron]], in the [[Kidney|kidney]], made of a [[Capillary|capilliary]] which is wound in a tight knot structure&nbsp;<ref>Grant's Atlas of Anatomy, Thirteenth Edition, 2001. A.M.R.Agur, A.F.Dalley.</ref>.&nbsp; The glomerulus is surrounded by a cup-like structure known as the [[Bowman's capsule|Bowman's Capsule]]&nbsp;and it&nbsp;is the first stage of filtration&nbsp;of the [[Blood|blood]] as it is entering the [[Kidney|kidney]]. [[Blood|Blood]] from the afferent arteriole enters the glomerulus and is put under high amounts of [[Blood pressure|pressure]] to force [[Molecules|molecules]] out of the [[Blood|blood]] stream and into the [[Bowman's capsule|Bowman's Capsule]] as the first stage of ultrafiltration. The efferent arteriole has a very narrow [[Lumen|lumen]], in order to maintain the high [[Blood pressure|pressure]] created, enough so that it will force [[Molecules|molecules]] out of the [[Plasma|plasma]] into the Bowman's space. Together, the glomerulus and the [[Bowman's capsule|Bowman's Capsule]] form what is known as the renal corpuscle&nbsp;<ref>Wheater's Functional Histology A Text and Colour Atlas, Fifth Edition 2006. B.Young, J.S.Lowe, A.Stevens, J.W.Heath.</ref>.&nbsp;<br>  
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The glomerulus is the beginning section of the [[Nephron|nephron]], in the [[Kidney|kidney]], made of a globular&nbsp;[[Capillary|capilliary]]&nbsp;network which is wound in a tight knot structure&nbsp;<ref>Grant's Atlas of Anatomy, Thirteenth Edition, 2001. A.M.R.Agur, A.F.Dalley.</ref>.&nbsp; The glomerulus is surrounded by a cup-like structure made of epithelial cells known as the [[Bowman's capsule|Bowman's Capsule]]&nbsp;and it&nbsp;is the first stage of filtration&nbsp;of the [[Blood|blood]] as it is entering the [[Kidney|kidney<ref>Stevens A; Lowe J Human Histology 3rd ed 2005, Elsevier Limited p298</ref>]]. The space between the capillary network and the capsule is continuous with lumen of the tubular system of the nephron, and is where the filtrate runs through<ref>Stevens A; Lowe J Human Histology 3rd ed 2005, Elsevier Limited p298</ref>. Coating the capillary network are podocytes, as well as an unusually thick basement membrane<ref>Stevens A; Lowe J Human Histology 3rd ed 2005, Elsevier Limited p298</ref>.&nbsp;[[Blood|Blood]] from the afferent arteriole enters the glomerulus and is put under high amounts of [[Blood pressure|pressure]] to force [[Molecules|molecules]] out of the [[Blood|blood]] stream and into the [[Bowman's capsule|Bowman's Capsule]] as the first stage of ultrafiltration. The efferent arteriole has a very narrow [[Lumen|lumen]], in order to maintain the high [[Blood pressure|pressure]] created, enough so that it will force [[Molecules|molecules]] out of the [[Plasma|plasma]] into the Bowman's space. Together, the glomerulus and the [[Bowman's capsule|Bowman's Capsule]] form what is known as the renal corpuscle&nbsp;<ref>Wheater's Functional Histology A Text and Colour Atlas, Fifth Edition 2006. B.Young, J.S.Lowe, A.Stevens, J.W.Heath.</ref>.&nbsp;<br>  
  
 
=== References  ===
 
=== References  ===
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Revision as of 21:32, 28 November 2013

The glomerulus is the beginning section of the nephron, in the kidney, made of a globular capilliary network which is wound in a tight knot structure [1].  The glomerulus is surrounded by a cup-like structure made of epithelial cells known as the Bowman's Capsule and it is the first stage of filtration of the blood as it is entering the kidneyUNIQ2c7a10e1504774d6-nowiki-00000004-QINU2UNIQ2c7a10e1504774d6-nowiki-00000005-QINU. The space between the capillary network and the capsule is continuous with lumen of the tubular system of the nephron, and is where the filtrate runs through[3]. Coating the capillary network are podocytes, as well as an unusually thick basement membrane[4]Blood from the afferent arteriole enters the glomerulus and is put under high amounts of pressure to force molecules out of the blood stream and into the Bowman's Capsule as the first stage of ultrafiltration. The efferent arteriole has a very narrow lumen, in order to maintain the high pressure created, enough so that it will force molecules out of the plasma into the Bowman's space. Together, the glomerulus and the Bowman's Capsule form what is known as the renal corpuscle [5]

References

  1. Grant's Atlas of Anatomy, Thirteenth Edition, 2001. A.M.R.Agur, A.F.Dalley.
  2. Stevens A; Lowe J Human Histology 3rd ed 2005, Elsevier Limited p298
  3. Stevens A; Lowe J Human Histology 3rd ed 2005, Elsevier Limited p298
  4. Stevens A; Lowe J Human Histology 3rd ed 2005, Elsevier Limited p298
  5. Wheater's Functional Histology A Text and Colour Atlas, Fifth Edition 2006. B.Young, J.S.Lowe, A.Stevens, J.W.Heath.


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