Glycosylation

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(Sugar residues are most commonly added the -NH2 of a Asn on the non-cystolic surface. They are transferred by a lipid (Dolichol) to the target and then trimmed and packaged.)
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= Glycosylation =
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Glycosylation is the process of adding [[sugars|sugars]]&lt;/a&gt; onto a [[protein|protein]], [[lipid|lipid]] or any organic molecule&nbsp;<ref>Ajit Varki et al. (2009 Essentials of Glycobiology, Second Edition, Cold Spring Harbour (NY): Cold Spring Laboratory Press , Chapter1</ref>&nbsp;<ref>Alberts et al., (2008) Molecular Biology of the cell, 5th edition New York: Garland science. Pg 776</ref>.&nbsp;Glucosylation is&nbsp;catalysed by enzymes&nbsp;called&nbsp;[[glycosyltransferases|glycosyltransferases]] <ref>Ajit Varki et al. (2009 Essentials of Glycobiology, Second Edition, Cold Spring Harbour (NY): Cold Spring Laboratory Press , Chapter1</ref>,&nbsp;in the lumen of the [[endoplasmic reticulum|endoplasmic reticulum]]&nbsp;and the [[Golgi_Apparatus|Golgi complex]]<ref>Berg et al.,(2006) Biochemistry, 6th edition, New York. Pg 317</ref>.<br>
  
Glycosylation is the process of adding [[Sugars|sugars]] onto a [[Protein|protein]], lipid or any organic molecule&nbsp;<ref>Ajit Varki et al. (2009 Essentials of Glycobiology, Second Edition, Cold Spring Harbour (NY): Cold Spring Laboratory Press , Chapter1</ref>&nbsp;<ref name="null">Alberts et al., (2008) Molecular Biology of the cell, 5th edition New York: Garland science. Pg 776</ref>.&nbsp;Glucosylation is&nbsp;catalysed by enzymes&nbsp;called&nbsp;glycosyltransferases <ref>Ajit Varki et al. (2009 Essentials of Glycobiology, Second Edition, Cold Spring Harbour (NY): Cold Spring Laboratory Press , Chapter1</ref>,&nbsp;in the lumen of the [[Endoplasmic Reticulum|endoplasmic reticulum]] and the Golgi complex<ref>Berg et al.,(2006) Biochemistry, 6th edition, New York. Pg 317</ref>.<br>
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=== References  ===
  
<h3> References  </h3>
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Latest revision as of 02:45, 25 October 2013

Glycosylation is the process of adding sugars</a> onto a protein, lipid or any organic molecule [1] [2]. Glucosylation is catalysed by enzymes called glycosyltransferases [3], in the lumen of the endoplasmic reticulum and the Golgi complex[4].

References

  1. Ajit Varki et al. (2009 Essentials of Glycobiology, Second Edition, Cold Spring Harbour (NY): Cold Spring Laboratory Press , Chapter1
  2. Alberts et al., (2008) Molecular Biology of the cell, 5th edition New York: Garland science. Pg 776
  3. Ajit Varki et al. (2009 Essentials of Glycobiology, Second Edition, Cold Spring Harbour (NY): Cold Spring Laboratory Press , Chapter1
  4. Berg et al.,(2006) Biochemistry, 6th edition, New York. Pg 317

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