Goldman equation

From The School of Biomedical Sciences Wiki
Revision as of 15:27, 15 November 2010 by 090012763 (Talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

Goldman equation is an equation used to calculate the electrical equilibium potential across the cell's membrane in the presence of more than one ions taking into account the selectivity of membrane's permeability. It is derived from the Nernst equation.


The Goldman equation can be expressed as follows:

Goldman eqn1.png


Goldman eqn2.png


Em is the potential difference of an ion between membranes

R is the universal gas constant; R = 8.314471 J mol-1

T is the thermodynamics temperature, in Kelvin; 0 K = -273.15oC

z is the number of moles of electrons transferred between membranes (defined by the valency of ion)

F is the Faraday's constant; F = 96,485.3415 C mol-1

PA or B is the permeability of the membrane to a particular ion (A or B)

[A or B]o is the concentration of ion outside the membrane

[A or B]i is the concentration of ion inside the membrane

See also


Personal tools