The Golgi apparatus is an organelle located near the nucleus. It consists of a stack of membrane-bound sacs called cisternae. It is known as the sorting centre for proteins destined for secretion which arrive from the endoplasmic reticulum. Inside the Golgi proteins undergo further post-translational modification such as trimming of core oligosaccharides as well as addition and removal of sugars. Proteins leaving the Golgi apparatus are directed to the appropriate destination depending on their function, including the cell surface, a lysosome or a secretory vesicle. The structure of the Golgi consists of a cis face at which the proteins enter and a trans face where the proteins leave. Early acting enzymes begin to interact at the cis face, whereas late acting enzymes interact at the trans face of the Golgi apparatus.
The Golgi apparatus is an internal organelle found near the nucleus of a eukaryotic cell. It is a stack of membrane-enclosed sacs called cisternae. Each stack contains 3-20 cisternae. The stack consists of the inner cis face and the outer trans face. Molecules synthesised in the Endoplasmic Reticulum enter the inner cis face via vesicles. Within the Golgi apparatus oligosaccharide groups are attached to the molecules. Molecules leave the Golgi via vesicles through the outer trans face and are transported to organelles or the plasma membrane.
- ↑ Albert, Bruce, Molecular biology of the cell, 5th Edition Garland Science, 2008