Gram-negative

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Gram-negative refers to a classification of bacteria based upon their cell wall structure. Gram-negative bacteria appear red as a result of [[Gram staining|Gram testing]], whereas&nbsp;[[Gram-positive]]&nbsp;stain purple.<br>
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See [[Gram_negative|Gram negative]]
 
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<u></u>The structure of the Gram-negative bacterial cell wall is what distinguishes it from Gram-positive bacteria. Gram-negative bacteria contain a much thinner layer of [[Peptidoglycan]]&nbsp;in comparison to a Gram-positive bacterial cell wall. The Gram-negative cell wall consists of a unique outer membrane, containing lipopolysaccharides, murein lipoproteins and porin channels. There is also a periplasmic space between the peptidoglycan cell wall, and the cell membrane.
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Gram-negative bacteria exhibit stronger resistance to [[Antibiotics]]&nbsp;such as [[Lysozyme]]&nbsp;and [[pennicillin|pennicillin]] G, as well as greater resistance to dyes and detergents.&nbsp; The lipopolysaccharide consists of a core [[polysaccharide|polysaccharide]], Lipid A and O-antigen. This lipolysaccharide layer is important in excluding large hydrophobic susbstances from interacting with the cell. Lipid A attaches to the outer membrane ensuring that the [[lipopolysaccharide|lipopolysaccharide]] remains attached to the cell&nbsp;<ref>Oh S., Antibiotics Attack (http://www.hhmi.org/biointeractive/Antibiotics_Attack/bb_2.html), July 1999, Montgomery Blair</ref>.<br>
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=== References  ===
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<references />
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Revision as of 01:31, 15 October 2013

See Gram negative

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