Gram positive bacteria
Bacteria can be categorised based upon their reaction to Gram stain, which is retained by cells with a thick layer of peptidoglycan on the outside of their cytoplasmic membrane; these cells are Gram-positive and stain purple. Bacteria which don't retain Gram stain are called Gram negative.
Gram-positive bacteria lack an outer membrane so are, on the whole, usually sensitive to beta-lactam antibiotics like penicillin, which interfere with the production of peptidoglycan, leaving the cytoplasmic membrane exposed, and the cell susceptible to lysis.
- ↑ https://www.sciencedirect.com/science/article/pii/B9780126775303502221
- ↑ Rang, H., Ritter, H., Flower, R., Henderson, G. (2016). Rang &amp; Dale's pharmacology (Eighth ed.)
- ↑ Madigan, M., Bender, K., Buckley, D., Sattley, W., Stahl, D. (2019). Brock biology of microorganisms (Fifteenth edition, Global ed.)