Helper T-cells

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(Created page with " <u>'''Definition:'''</u> Helper T cells ha'''<u></u>'''ve the function to help other immune cells through the production and secretion of cytokines. These [[|T cells]] can ...")
 
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&nbsp;<u>'''Definition:'''</u> Helper T cells ha'''<u></u>'''ve the function to help other immune cells through the production and secretion of cytokines. These [[T cells]] can be divided into different subsets. The subsets are based on the expression of particular surface markers and on the cytokine production of the helper T cell.&nbsp;
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Helper T cells have the function to help other immune cells through the production and secretion of cytokines. These [[T cells]] can be divided into different subsets. The subsets are based on the expression of particular surface markers and on the cytokine production of the helper T cell.  
  
<u>'''Types of Helper T Cells:&nbsp;'''</u>
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=== Types of Helper T Cells ===
  
&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;-&gt;&nbsp;'''CD 4-expressing T Helper Cells:''' They help [[B cells]] and to assist them in the process of differentiation into plasma cells. Helper T cells are able to do that by producing and secreting cytokines like [[IL-4]]. In addition, in order to help the particular B cell, the T cell has to be in direct contact with it.&nbsp;
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*'''CD 4-expressing T Helper Cells:''' They help [[B cells]] and to assist them in the process of differentiation into plasma cells. Helper T cells are able to do that by producing and secreting cytokines like [[IL-4]]. In addition, in order to help the particular B cell, the T cell has to be in direct contact with it.  
 
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*'''TH1 Helper Cells:''' These helper cells secrete TNF and interferon gamma. "TNF" stands for tumour necrosis factor. Interferon-gamma helps with the activation of macrophages and stimulation of an inflammatory response. In addition, TH1 helper cells produce antibodies, such as IgG1 and IgG3. &lt;u&lt;/u&gt;
&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;-&gt; '''TH1 Helper Cells:''' These helper cells secrete TNF and interferon gamma. "TNF" stands for tumor necrosis factor. Interferon gamma helps with the activation of macrophages and stimulation of an inflammatory response. In addition, TH1&nbsp; helper cells produce antibodies, such as IgG1 and IgG3.&nbsp;<u</u>
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*'''TH2 Helper Cells:''' These helper cells secrete [[IL-10]] and IL-4. IL-4 aids B cell class switching to the IgE and IgG1 isotypes.  
 
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*'''TH17 Helper Cells:''' These helper cells secrete [[IL-17]].
&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;-&gt; '''TH2 Helper Cells:''' These helper cells secrete [[IL-10]] and IL-4. IL-4 aids B cell class switching to the IgE and IgG1 isotypes.&nbsp;
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&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;-&gt; '''TH17 Helper Cells:''' These helper cells secrete [[IL-17]].
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Revision as of 17:27, 22 October 2018

Helper T cells have the function to help other immune cells through the production and secretion of cytokines. These T cells can be divided into different subsets. The subsets are based on the expression of particular surface markers and on the cytokine production of the helper T cell.

Types of Helper T Cells

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