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Homozygote refers to a pair of identical alleles of a gene. It means the organism or the cell is having same allele for a gene. It can be homozygous dominant or homozygous recessive[1].

For example, for a certain gene, "A" represents the dominant allele and "a" represents the recessive allele. The combination of "AA" and "aa" will be a homozygote allele pair which represents homozygous dominant and homozygous recessive respectively. Homozygous recessive genotypes are used in "test cross" for the analysis and determination of a unknown genotype.[2]


  1. Alberts, B. et al., 2008, Molecular Biology of The Cell, 5th edition, Garland Science, New York. Pg. G:18.
  2. Robert, H., et Al., 2013, Practical Skills in Biomolecular Sciences, 4th edition, Gosport:Pearson Education Limited 2013.
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