Induced fit mechanism

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The substrate approaches the enzyme's active site and binds to it. The binding induces the active site to change its shape to fit complementary to the substrate [1]. When the catalytic reaction terminates, the products leave the active site and the enzyme returns to its original configuration.

Reference

  1. Berg,J.M.,Tymoczko,J.L.,Stryer,L.(2007)Biochemistry, sixth ed, New York:W.H. Freeman and Company,pp.215
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