Ischemia

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Ischemia occurs when plaque hardens and forms a clot in the arteries. As a result, the blood flow through the arteries is reduced. The plaque itself is made up of metabolic waste products formed through an ischemic cascade[1]. In the case of cardiac ischemia, the blood flow to the heart is decreased thus leading to myocardial infarction[2].

Cardiac Ischemia can be caused by many things such as an unheathy lifestyle (i.e. smoking and obesity). Proir to Ischemia causing a heart attack, patients may have symptoms such as swelling in the limbs or fatique but can often show no symptoms until a myocardial infarction occurs. [3] This is also known as Silent Ischemia.[4]

References

  1. 'Pathophysiologic cascades in ischemic stroke' Int J Stroke. 2012 Jul; 7(5): 378–385
  2. http://www.webmd.com
  3. https://www.healthline.com/health/ischemic-cardiomyopathy#symptoms2
  4. http://www.heart.org/HEARTORG/Conditions/HeartAttack/TreatmentofaHeartAttack/Silent-Ischemia-and-Ischemic-Heart-Disease_UCM_434092_Article.jsp#.We9ODWhSzIU
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