Isomerase

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Isomerase is a type of enzyme that catalyses isomeration reactions[1]. In these reactions, a molecule's structure is altered, but the molecular formula and the number of atoms stay the same.

An example of this is phosphoglucose isomerase which is important in the process of glycolysis, where it catalyses the isomeration of glucose-6-phosphate to fructose-6-phosphate.

More examples of isomerase would be Alanine racemase and mutarotase catalyzes. Alanine racemase converts L-alanine into D-alanine. Mutarotase catalyzes converts α-D-glucose into β-D-glucose[2].

Phosphoglucose isomerase is also a key enzyme involved in the process of gluconeogenesis[2]   

[3]

  1. Berg J.M., 2012. Biochemistry, 7th Edition. W. H. Freeman and Company Publishing.
  2. Britannica, https://www.britannica.com/science/isomerase, Date accessed- 3/12/18
  3. http://www.ebi.ac.uk/interpro/entry/IPR001672
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