Kinase

From The School of Biomedical Sciences Wiki
(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
A kinase is an [[Enzyme|enzyme]] that catalyzes the addition of&nbsp;[[Phosphate|phosphate groups]]&nbsp;(phosphorylation) to specific substrates&nbsp;<ref>Molecular biology of the cell (5th edition), Alberts et al. Garland Science, 2008</ref>. There are currently 518 known protein kinase genes in the human genome.<ref name="null">Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S (2002) The protein kinase complement of the human genome. Science 298: 1912-1934</ref>  
+
A kinase is an [[Enzyme|enzyme]] that catalyses the addition of&nbsp;[[Phosphate|phosphate groups]]&nbsp;(phosphorylation) to specific substrates, forming a covalent bond with this substrate&nbsp;<ref>Molecular biology of the cell (5th edition), Alberts et al. Garland Science, 2008</ref>. There are currently 518 known protein kinase genes in the human genome.<ref name="null">Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S (2002) The protein kinase complement of the human genome. Science 298: 1912-1934</ref>Furthermore, kinases are commonly found in cell signalling pathways.
  
=== References  ===
+
=== References<references /> ===
  
 
<references />  
 
<references />  
  
 
<references /><br>
 
<references /><br>

Revision as of 20:42, 26 November 2011

A kinase is an enzyme that catalyses the addition of phosphate groups (phosphorylation) to specific substrates, forming a covalent bond with this substrate [1]. There are currently 518 known protein kinase genes in the human genome.[2]Furthermore, kinases are commonly found in cell signalling pathways.

References
  1. Molecular biology of the cell (5th edition), Alberts et al. Garland Science, 2008
  2. Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S (2002) The protein kinase complement of the human genome. Science 298: 1912-1934



Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox