A microtubule motor protein first discovered in the giant axon of the quid, kinesins hydrolyse ATP to produce energy to move membrane-bound organelles along microtubules. Kinesins carry the membrane-bound organelles away from the neuronal cell body and towards the axon terminal. If mutations occur in kinesins can lead to disorders in the nervous system. This movement is towards the positive end of the microtubule unlike dyneins, another type of microtubule motor protein which carry membrane-bound organelles towards the negative end of microtubules.
- ↑ Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Section 34.3, Kinesin and Dynein Move Along Microtubules.
- ↑ Alberts B., Johnson A., Lewis J., Raff M., Roberts K., Walter P. (2008) "Molecular Biology of the Cell, Page 1014 " 5th edition, New York, Garland Science