These are organs where lymphocytes develop, proliferate and undergo gene rearrangement. There are two sub-categories of lymphoid organs. The Central/ primary lymphoid organs this is where lymphocytes are synthesized, these organs include the bone marrow and thymus, and are located in the upper chest. The peripheral/ secondary lymphoid organ, which is where mature naive lymphocytes are managed and the specific immune response commence; these organs include lymph nodes, the nasal and respiratory tract, the urogenital tract etc.
- ↑ Murphy, K., Weaver, C. (2017). Janeway's Immunobiology (9th ed.). New York: Garland Science.