Macrophage

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A cellular element of the innate immune system, these phagocytic white blood cells are the first to respond to infection. They also play a role in inflammation of tissues. When activated, they become antigen presenting cells as well as producing chemokines and cytokines [1]. They work by engulfing pathogens detected by the immune system and engulfing them. The newly engulfed pathogen is then bound to a phagosome and lysosome which release enzymes and toxic chemicals that digest the pathogen.

References

  1. Janeways ImmunoBiology, Murphy K. et al., 2008, 7th ed.
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