# Michaelis menten equation

From The School of Biomedical Sciences Wiki

The Michaelis-Menten equation is used to work out the **rate** **of enzyme reactions** and is written as follows:

** V = V_{max} [S]**

** K _{m} + [S]**

**V**_{max} is the maximum rate of an enzyme reaction, occurs when all substrate is saturated.

**K _{m}** is the Michaelis-Menten constant and is the substrate concentration at half V

_{max }. (Higher the Km value, lower the affinity)

_{}V_{max} and K_{m} can also be shown on a graph, the graph which shows this best is a **double reciprocal plot **(Lineweaver-Burk plot). You can obtain the results by plotting 1/V against 1/[S] ^{[1]}.

### References

- ↑ Molecular Biology of the Cell, Alberts et al., 5th Edition (2007) Garland Science, New York Chapter 3 p162-163