Mitotic spindles

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Mitotic spindles are all the spindle fibres that are formed at the beginning of the metaphase stage within mitosis. The end of the spindles are located at the centrosomes. They attach to kinetochores which are present in the same relative position on the chromosomes to the centromere. This allows the mitotic spindle to pull the sister chromatids to opposite poles and therefore after cytokinesis occurs there will be one sister chromatid in each of the daughter cells.[1] The spindle fibres consist mostly of microtubules, which are hollow cylinders that contain the protein tubulin - the structure of microtubules thus mitotic spindles are very rigid.[2]


  1. Hartl,D.L. and Jones, E.W. (2009) Genetics: Analysis of Genes and Genomes. 7th Edition. Sudbury: Jones and Bartlett Page 117.
  2. Alberts, B., Bray, D., Hopkin, K., Johnson, A., Lewis, J., Raff, M., Roberts, K., Walter, P. (2011) Essential Cell Biology. 4th Edition. New York: Garland Science. Page 566.
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